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Camptothecin 98% Camptotheca Acuminata Extract Powder CAS:7689-03-4

Camptothecin (CPT) is a cytotoxic quino line alkaloid which inhibits the DNA enzyme topoisomerase I (topo I).

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Description
Specification

Camptotheca Acuminata Extract Powder CAS:7689-03-4

Basic info.

 

Certification: ISO, FDA
Assay Method: HPLC
Application Form: Powder
Application: Food, Health Care Products, Medicine
State: Powder
Extract Source: Camptotheca Acuminata Extract

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Product Description

Product name: Camptothecin
CAS No. :7689-03-4
Molecular formula: C20H16N2O4
Molecular weight: 348.36
Specification: 98%,99% Camptothecin
Test method: HPLC
Appearance: Light yellow crystal powder
Source: Camptotheca Acuminata Decne's leaf
Grade: Pharmaceutical and food

test report 

Items

Standards

Results

Physical Analysis

Description

Light Yellow Powder Complies

Assay

98% 98.2%

Mesh Size

100 % pass 80 mesh Complies

Ash

≤ 5.0% 2.85%
Loss on Drying ≤ 5.0% 2.85%
Chemical Analysis
Heavy Metal ≤ 10.0 mg/kg Complies
Pb ≤ 2.0 mg/kg Complies
As ≤ 1.0 mg/kg Complies
Hg ≤ 0.1 mg/kg Complies
Microbiological Analysis
Residue of Pesticide Negative Negative
Total Plate Count ≤ 1000cfu/g Complies
Yeast&Mold ≤ 100cfu/g Complies
E.coil Negative Negative
Salmonella Negative Negative

 


Denifiton

  • Camptothecin (CPT) is a cytotoxic quino line alkaloid which inhibits the DNA enzyme topoisomerase I (topo I). It was discovered in 1966 by M. E. Wall and M. C. Wani in systematic screening of natural products for anticancer drugs. It was isolated from the bark and stem of Camptotheca acuminata (Camptotheca, Happy tree), a tree native to China used as a cancer treatment in Traditional Chinese Medicine. CPT showed remarkable anticancer activity in preliminary clinical trials but also low solubility and (high) adverse drug reaction. Because of these disadvantages synthetic and medicinal chemists have developed numerous syntheses of Camptothecin and various derivatives to increase the benefits of the chemical, with good results. Two CPT analogues have been approved and are used in cancer chemotherapy today, topotecan and irinotecan.

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Application

  • As Food and beverage ingredients.

  • As Healthy Products ingredients.

  • As Nutrition Supplements ingredients.

  • As Pharmaceutical Industry & General Drugs ingredients.

  • As a health food and cosmetic ingredients.



Camptotheca Acuminata Extract Powder CAS:7689-03-4


Product Overview

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